GET3 protein (Chlorocebus sabaeus) - STRING interaction network

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GET3

ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...] (348 aa)

Predicted Functional Partners:

GET4

0.980

GET1

0.973

CAMLG

0.960

STX5

0.880

SGTB

0.880

UBL4A

0.853

UBL4B

0.853

SGTA

0.842

ENSCSAP00000003114

0.811

ENSCSAP00000008966

0.789

Your Current Organism:

Chlorocebus sabaeus

NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CAMLG	GET1	ENSCSAP00000009619	ENSCSAP00000004591	Calcium signal-modulating cyclophilin ligand; Likely involved in the mobilization of calcium as a result of the TCR/CD3 complex interaction. Binds to cyclophilin B.	Guided entry of tail-anchored proteins factor 1.	0.994
CAMLG	GET3	ENSCSAP00000009619	ENSCSAP00000002872	Calcium signal-modulating cyclophilin ligand; Likely involved in the mobilization of calcium as a result of the TCR/CD3 complex interaction. Binds to cyclophilin B.	ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]	0.960
CAMLG	GET4	ENSCSAP00000009619	ENSCSAP00000013572	Calcium signal-modulating cyclophilin ligand; Likely involved in the mobilization of calcium as a result of the TCR/CD3 complex interaction. Binds to cyclophilin B.	Guided entry of tail-anchored proteins factor 4.	0.644
CAMLG	SGTA	ENSCSAP00000009619	ENSCSAP00000007693	Calcium signal-modulating cyclophilin ligand; Likely involved in the mobilization of calcium as a result of the TCR/CD3 complex interaction. Binds to cyclophilin B.	Small glutamine rich tetratricopeptide repeat containing alpha.	0.729
CAMLG	STX5	ENSCSAP00000009619	ENSCSAP00000003033	Calcium signal-modulating cyclophilin ligand; Likely involved in the mobilization of calcium as a result of the TCR/CD3 complex interaction. Binds to cyclophilin B.	Syntaxin 5; Belongs to the syntaxin family.	0.452
CAMLG	UBL4A	ENSCSAP00000009619	ENSCSAP00000003029	Calcium signal-modulating cyclophilin ligand; Likely involved in the mobilization of calcium as a result of the TCR/CD3 complex interaction. Binds to cyclophilin B.	Ubiquitin like 4A.	0.738
ENSCSAP00000003114	GET3	ENSCSAP00000003114	ENSCSAP00000002872	LMWPc domain-containing protein.	ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]	0.811
ENSCSAP00000008966	GET3	ENSCSAP00000008966	ENSCSAP00000002872	RING-type domain-containing protein.	ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]	0.789
ENSCSAP00000008966	GET4	ENSCSAP00000008966	ENSCSAP00000013572	RING-type domain-containing protein.	Guided entry of tail-anchored proteins factor 4.	0.832
ENSCSAP00000008966	SGTA	ENSCSAP00000008966	ENSCSAP00000007693	RING-type domain-containing protein.	Small glutamine rich tetratricopeptide repeat containing alpha.	0.527
ENSCSAP00000008966	UBL4A	ENSCSAP00000008966	ENSCSAP00000003029	RING-type domain-containing protein.	Ubiquitin like 4A.	0.467
ENSCSAP00000008966	UBL4B	ENSCSAP00000008966	ENSCSAP00000017826	RING-type domain-containing protein.	Ubiquitin like 4B.	0.467
GET1	CAMLG	ENSCSAP00000004591	ENSCSAP00000009619	Guided entry of tail-anchored proteins factor 1.	Calcium signal-modulating cyclophilin ligand; Likely involved in the mobilization of calcium as a result of the TCR/CD3 complex interaction. Binds to cyclophilin B.	0.994
GET1	GET3	ENSCSAP00000004591	ENSCSAP00000002872	Guided entry of tail-anchored proteins factor 1.	ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]	0.973
GET1	GET4	ENSCSAP00000004591	ENSCSAP00000013572	Guided entry of tail-anchored proteins factor 1.	Guided entry of tail-anchored proteins factor 4.	0.710
GET1	SGTA	ENSCSAP00000004591	ENSCSAP00000007693	Guided entry of tail-anchored proteins factor 1.	Small glutamine rich tetratricopeptide repeat containing alpha.	0.867
GET1	SGTB	ENSCSAP00000004591	ENSCSAP00000012012	Guided entry of tail-anchored proteins factor 1.	Small glutamine rich tetratricopeptide repeat containing beta.	0.604
GET1	STX5	ENSCSAP00000004591	ENSCSAP00000003033	Guided entry of tail-anchored proteins factor 1.	Syntaxin 5; Belongs to the syntaxin family.	0.579
GET1	UBL4A	ENSCSAP00000004591	ENSCSAP00000003029	Guided entry of tail-anchored proteins factor 1.	Ubiquitin like 4A.	0.895
GET1	UBL4B	ENSCSAP00000004591	ENSCSAP00000017826	Guided entry of tail-anchored proteins factor 1.	Ubiquitin like 4B.	0.457

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