Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TNKS2Poly [ADP-ribose] polymerase. (1166 aa)    
Predicted Functional Partners:
TNKS
Poly [ADP-ribose] polymerase.
   
  0.964
TERF1
Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat.
    
 0.958
RNF146
Ring finger protein 146.
    
 0.922
AXIN1
Axin 1.
    
 0.907
BABAM1
BRISC and BRCA1 A complex member 1.
    
 0.897
AXIN2
Axin 2.
    
 0.896
GMDS
NAD(P)-bd_dom domain-containing protein.
    
 
 0.881
PARP3
Poly [ADP-ribose] polymerase.
   
 
 0.865
LNPEP
Leucyl and cystinyl aminopeptidase.
   
 
 0.848
SH3BP2
SH3 domain binding protein 2.
    
 
 0.819
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
Server load: medium (44%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.