DHPS protein (Chlorocebus sabaeus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

DHPS

Uncharacterized protein. (369 aa)

Predicted Functional Partners:

EIF5A2

0.989

EIF5A

0.978

DOHH

0.969

MAPK3

0.910

RPL9

0.816

MAPK1

0.758

CYTB

0.725

DHFR

0.684

SH3BP5

0.653

FARSA

0.652

Your Current Organism:

Chlorocebus sabaeus

NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CYTB	DHFR	ENSCSAP00000000013	ENSCSAP00000011219	Cytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.	Dihydrofolate reductase; Belongs to the dihydrofolate reductase family.	0.717
CYTB	DHPS	ENSCSAP00000000013	ENSCSAP00000002895	Cytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.	Uncharacterized protein.	0.725
DHFR	CYTB	ENSCSAP00000011219	ENSCSAP00000000013	Dihydrofolate reductase; Belongs to the dihydrofolate reductase family.	Cytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.	0.717
DHFR	DHPS	ENSCSAP00000011219	ENSCSAP00000002895	Dihydrofolate reductase; Belongs to the dihydrofolate reductase family.	Uncharacterized protein.	0.684
DHPS	CYTB	ENSCSAP00000002895	ENSCSAP00000000013	Uncharacterized protein.	Cytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.	0.725
DHPS	DHFR	ENSCSAP00000002895	ENSCSAP00000011219	Uncharacterized protein.	Dihydrofolate reductase; Belongs to the dihydrofolate reductase family.	0.684
DHPS	DOHH	ENSCSAP00000002895	ENSCSAP00000007384	Uncharacterized protein.	Deoxyhypusine hydroxylase; Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor; Belongs to the deoxyhypusine hydroxylase family.	0.969
DHPS	EIF5A	ENSCSAP00000002895	ENSCSAP00000008020	Uncharacterized protein.	eIF-5a domain-containing protein.	0.978
DHPS	EIF5A2	ENSCSAP00000002895	ENSCSAP00000008899	Uncharacterized protein.	Eukaryotic translation initiation factor 5A.	0.989
DHPS	FARSA	ENSCSAP00000002895	ENSCSAP00000002819	Uncharacterized protein.	Phenylalanyl-tRNA synthetase subunit alpha.	0.652
DHPS	MAPK1	ENSCSAP00000002895	ENSCSAP00000009828	Uncharacterized protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.758
DHPS	MAPK3	ENSCSAP00000002895	ENSCSAP00000002490	Uncharacterized protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.910
DHPS	RPL9	ENSCSAP00000002895	ENSCSAP00000012982	Uncharacterized protein.	Ribosomal protein L9.	0.816
DHPS	SH3BP5	ENSCSAP00000002895	ENSCSAP00000006400	Uncharacterized protein.	SH3 domain binding protein 5.	0.653
DOHH	DHPS	ENSCSAP00000007384	ENSCSAP00000002895	Deoxyhypusine hydroxylase; Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor; Belongs to the deoxyhypusine hydroxylase family.	Uncharacterized protein.	0.969
DOHH	EIF5A	ENSCSAP00000007384	ENSCSAP00000008020	Deoxyhypusine hydroxylase; Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor; Belongs to the deoxyhypusine hydroxylase family.	eIF-5a domain-containing protein.	0.983
DOHH	EIF5A2	ENSCSAP00000007384	ENSCSAP00000008899	Deoxyhypusine hydroxylase; Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor; Belongs to the deoxyhypusine hydroxylase family.	Eukaryotic translation initiation factor 5A.	0.988
EIF5A	DHPS	ENSCSAP00000008020	ENSCSAP00000002895	eIF-5a domain-containing protein.	Uncharacterized protein.	0.978
EIF5A	DOHH	ENSCSAP00000008020	ENSCSAP00000007384	eIF-5a domain-containing protein.	Deoxyhypusine hydroxylase; Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L- lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor; Belongs to the deoxyhypusine hydroxylase family.	0.983
EIF5A	EIF5A2	ENSCSAP00000008020	ENSCSAP00000008899	eIF-5a domain-containing protein.	Eukaryotic translation initiation factor 5A.	0.969

page 1 of 2

Server load: low (34%) [HD]

Permalink

Network

Neighborhood

Experiments

Co-occurrence

Databases

Co-expression

Textmining

Fusion

© STRING Consortium 2026

Credits

Access

Info

About