Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADAM8ADAM metallopeptidase domain 8. (824 aa)    
Predicted Functional Partners:
DOCK8
Dedicator of cytokinesis 8; Belongs to the DOCK family.
   
  
 0.623
MRPL13
Mitochondrial ribosomal protein L13; Belongs to the universal ribosomal protein uL13 family.
      
 0.564
S100A12
S100 calcium binding protein A12; Belongs to the S-100 family.
   
  
 0.561
PLEC
Plectin.
     
 0.560
SERPINB10
Serpin family B member 10; Belongs to the serpin family.
     
 0.559
MMP9
Matrix metallopeptidase 9.
   
  
 0.551
MMP12
Matrix metallopeptidase 12.
   
  
 0.512
MMP25
Matrix metallopeptidase 25.
   
  
 0.503
ADAM2
ADAM metallopeptidase domain 2.
  
 
0.496
TMPRSS13
Transmembrane serine protease 13; Belongs to the peptidase S1 family.
   
 
 0.490
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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