STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KCNH2Potassium voltage-gated channel subfamily H member 2. (1160 aa)    
Predicted Functional Partners:
HSP90AA1
HATPase_c domain-containing protein.
    
 
 0.841
KCNE3
Potassium voltage-gated channel subfamily E regulatory subunit 3.
     
 0.819
SCN5A
Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
    
 
 0.815
KCNE2
Potassium voltage-gated channel subfamily E regulatory subunit 2.
    
 0.813
KCNQ1
Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family.
   
 
 0.772
KCNAB2
Potassium voltage-gated channel subfamily A regulatory beta subunit 2.
    
 0.748
KCNE1
Uncharacterized protein.
    
 0.714
KCNE5
Potassium voltage-gated channel subfamily E regulatory subunit 5.
     
 0.709
CACNA1C
Calcium voltage-gated channel subunit alpha1 C.
    
 
 0.699
KCNJ2
Potassium voltage-gated channel subfamily J member 2.
      
 0.697
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.