STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IRAK1Interleukin 1 receptor associated kinase 1. (686 aa)    
Predicted Functional Partners:
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.999
MYD88
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
   
 0.998
TAB2
TGF-beta activated kinase 1 (MAP3K7) binding protein 2.
    
 0.998
IRAK4
Interleukin 1 receptor associated kinase 4.
  
0.996
IL1R1
Interleukin 1 receptor type 1.
    
 0.987
IRAK3
Interleukin 1 receptor associated kinase 3.
  
 
0.986
TAB3
TGF-beta activated kinase 1 (MAP3K7) binding protein 3.
    
 0.981
TAB1
TGF-beta activated kinase 1 (MAP3K7) binding protein 1.
   
 0.979
CHUK
Component of inhibitor of nuclear factor kappa B kinase complex.
   
0.978
IRF7
Interferon regulatory factor 7.
   
 0.977
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.