LDLR protein (Chlorocebus sabaeus) - STRING interaction network

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[Homology]

Score

LDLR

Low density lipoprotein receptor. (767 aa)

Predicted Functional Partners:

APOB

0.998

PCSK9

0.998

LDLRAP1

0.996

MYLIP

0.993

APOE

0.969

DAB2

0.955

HMGCS1

0.871

DAB1

0.862

RELN

0.857

SREBF2

0.844

Your Current Organism:

Chlorocebus sabaeus

NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APOB	APOE	ENSCSAP00000004392	ENSCSAP00000014799	Apolipoprotein B.	Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...]	0.988
APOB	DAB2	ENSCSAP00000004392	ENSCSAP00000012980	Apolipoprotein B.	DAB adaptor protein 2.	0.713
APOB	LDLR	ENSCSAP00000004392	ENSCSAP00000003140	Apolipoprotein B.	Low density lipoprotein receptor.	0.998
APOB	LDLRAP1	ENSCSAP00000004392	ENSCSAP00000017055	Apolipoprotein B.	Low density lipoprotein receptor adaptor protein 1.	0.888
APOB	PCSK9	ENSCSAP00000004392	ENSCSAP00000016701	Apolipoprotein B.	Proprotein convertase subtilisin/kexin type 9.	0.729
APOB	SREBF2	ENSCSAP00000004392	ENSCSAP00000002046	Apolipoprotein B.	Sterol regulatory element binding transcription factor 2.	0.409
APOE	APOB	ENSCSAP00000014799	ENSCSAP00000004392	Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...]	Apolipoprotein B.	0.988
APOE	LDLR	ENSCSAP00000014799	ENSCSAP00000003140	Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...]	Low density lipoprotein receptor.	0.969
APOE	LDLRAP1	ENSCSAP00000014799	ENSCSAP00000017055	Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...]	Low density lipoprotein receptor adaptor protein 1.	0.479
APOE	PCSK9	ENSCSAP00000014799	ENSCSAP00000016701	Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...]	Proprotein convertase subtilisin/kexin type 9.	0.486
APOE	RELN	ENSCSAP00000014799	ENSCSAP00000007805	Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...]	Reelin.	0.403
DAB1	LDLR	ENSCSAP00000016694	ENSCSAP00000003140	DAB adaptor protein 1.	Low density lipoprotein receptor.	0.862
DAB1	RELN	ENSCSAP00000016694	ENSCSAP00000007805	DAB adaptor protein 1.	Reelin.	0.924
DAB2	APOB	ENSCSAP00000012980	ENSCSAP00000004392	DAB adaptor protein 2.	Apolipoprotein B.	0.713
DAB2	LDLR	ENSCSAP00000012980	ENSCSAP00000003140	DAB adaptor protein 2.	Low density lipoprotein receptor.	0.955
DAB2	LDLRAP1	ENSCSAP00000012980	ENSCSAP00000017055	DAB adaptor protein 2.	Low density lipoprotein receptor adaptor protein 1.	0.924
DAB2	RELN	ENSCSAP00000012980	ENSCSAP00000007805	DAB adaptor protein 2.	Reelin.	0.484
HMGCS1	LDLR	ENSCSAP00000012828	ENSCSAP00000003140	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Low density lipoprotein receptor.	0.871
HMGCS1	SREBF2	ENSCSAP00000012828	ENSCSAP00000002046	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	Sterol regulatory element binding transcription factor 2.	0.754
LDLR	APOB	ENSCSAP00000003140	ENSCSAP00000004392	Low density lipoprotein receptor.	Apolipoprotein B.	0.998

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