| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| H2AC20 | LOC103221971 | ENSCSAP00000017778 | ENSCSAP00000018748 | Histone H2A; Belongs to the histone H2A family. | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.977 |
| H2AC20 | NAA40 | ENSCSAP00000017778 | ENSCSAP00000003174 | Histone H2A; Belongs to the histone H2A family. | N(alpha)-acetyltransferase 40, NatD catalytic subunit. | 0.639 |
| H2AC20 | SSRP1 | ENSCSAP00000017778 | ENSCSAP00000002249 | Histone H2A; Belongs to the histone H2A family. | FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] | 0.816 |
| LOC103221971 | H2AC20 | ENSCSAP00000018748 | ENSCSAP00000017778 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | Histone H2A; Belongs to the histone H2A family. | 0.977 |
| LOC103221971 | NAA40 | ENSCSAP00000018748 | ENSCSAP00000003174 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | N(alpha)-acetyltransferase 40, NatD catalytic subunit. | 0.736 |
| LOC103221971 | NAT10 | ENSCSAP00000018748 | ENSCSAP00000001695 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. | 0.501 |
| LOC103221971 | SSRP1 | ENSCSAP00000018748 | ENSCSAP00000002249 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] | 0.829 |
| LOC103221971 | XPC | ENSCSAP00000018748 | ENSCSAP00000005659 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | XPC complex subunit, DNA damage recognition and repair factor. | 0.495 |
| NAA20 | NAA30 | ENSCSAP00000007644 | ENSCSAP00000010636 | N(alpha)-acetyltransferase 20, NatB catalytic subunit. | N(alpha)-acetyltransferase 30, NatC catalytic subunit. | 0.855 |
| NAA20 | NAA40 | ENSCSAP00000007644 | ENSCSAP00000003174 | N(alpha)-acetyltransferase 20, NatB catalytic subunit. | N(alpha)-acetyltransferase 40, NatD catalytic subunit. | 0.739 |
| NAA20 | NAA50 | ENSCSAP00000007644 | ENSCSAP00000003077 | N(alpha)-acetyltransferase 20, NatB catalytic subunit. | N(alpha)-acetyltransferase 50, NatE catalytic subunit. | 0.859 |
| NAA20 | NAT10 | ENSCSAP00000007644 | ENSCSAP00000001695 | N(alpha)-acetyltransferase 20, NatB catalytic subunit. | RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. | 0.577 |
| NAA30 | NAA20 | ENSCSAP00000010636 | ENSCSAP00000007644 | N(alpha)-acetyltransferase 30, NatC catalytic subunit. | N(alpha)-acetyltransferase 20, NatB catalytic subunit. | 0.855 |
| NAA30 | NAA40 | ENSCSAP00000010636 | ENSCSAP00000003174 | N(alpha)-acetyltransferase 30, NatC catalytic subunit. | N(alpha)-acetyltransferase 40, NatD catalytic subunit. | 0.742 |
| NAA30 | NAA50 | ENSCSAP00000010636 | ENSCSAP00000003077 | N(alpha)-acetyltransferase 30, NatC catalytic subunit. | N(alpha)-acetyltransferase 50, NatE catalytic subunit. | 0.768 |
| NAA30 | NAT10 | ENSCSAP00000010636 | ENSCSAP00000001695 | N(alpha)-acetyltransferase 30, NatC catalytic subunit. | RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. | 0.560 |
| NAA40 | H2AC20 | ENSCSAP00000003174 | ENSCSAP00000017778 | N(alpha)-acetyltransferase 40, NatD catalytic subunit. | Histone H2A; Belongs to the histone H2A family. | 0.639 |
| NAA40 | LOC103221971 | ENSCSAP00000003174 | ENSCSAP00000018748 | N(alpha)-acetyltransferase 40, NatD catalytic subunit. | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.736 |
| NAA40 | NAA20 | ENSCSAP00000003174 | ENSCSAP00000007644 | N(alpha)-acetyltransferase 40, NatD catalytic subunit. | N(alpha)-acetyltransferase 20, NatB catalytic subunit. | 0.739 |
| NAA40 | NAA30 | ENSCSAP00000003174 | ENSCSAP00000010636 | N(alpha)-acetyltransferase 40, NatD catalytic subunit. | N(alpha)-acetyltransferase 30, NatC catalytic subunit. | 0.742 |