Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
TRIP12Thyroid hormone receptor interactor 12. (2067 aa)    
Predicted Functional Partners:
UBR1
E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
   
 0.974
UBR2
E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
   
 0.954
USP7
Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family.
   
 
 0.953
USP34
Ubiquitin specific peptidase 34; Belongs to the peptidase C19 family.
   
 
 0.932
RPS27A
Ubiquitin-like domain-containing protein.
    
 0.926
ENSCSAP00000017575
Ubiquitin-like domain-containing protein.
    
 0.926
ENSCSAP00000017765
Ubiquitin-like domain-containing protein.
    
 0.926
UBE2D1
Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.925
UBR5
Ubiquitin protein ligase E3 component n-recognin 5.
   
  
0.923
UBA52
Ubiquitin A-52 residue ribosomal protein fusion product 1.
   
  0.903
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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