Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
CUL1Cullin 1; Belongs to the cullin family. (776 aa)    
Predicted Functional Partners:
RBX1
Ring-box 1.
    
 0.999
FBXW11
F-box and WD repeat domain containing 11.
    
 0.999
SKP1
S-phase kinase associated protein 1; Belongs to the SKP1 family.
   
 0.999
BTRC
Beta-transducin repeat containing E3 ubiquitin protein ligase.
    
 0.998
SKP2
S-phase kinase associated protein 2.
    
 0.998
FBXL3
F-box and leucine rich repeat protein 3.
   
 0.994
CAND1
Cullin associated and neddylation dissociated 1.
   
 0.993
FBXO5
F-box protein 5.
    
 0.993
CDKN1B
Cyclin dependent kinase inhibitor 1B.
    
 0.989
FBXL5
F-box and leucine rich repeat protein 5.
    
 0.989
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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