STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NR1I2Nuclear receptor subfamily 1 group I member 2. (379 aa)    
Predicted Functional Partners:
NCOA1
Nuclear receptor coactivator.
    
 0.947
NCOR2
Nuclear receptor corepressor 2.
    
 0.864
CYP3A4
Cytochrome P450 family 3 subfamily A member 4; Belongs to the cytochrome P450 family.
   
 0.863
PPARGC1A
PPARG coactivator 1 alpha.
    
 0.818
RXRA
Retinoid X receptor alpha.
    
 
 0.810
MED1
Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    
 0.798
CYP2B6
Cytochrome P450 family 2 subfamily B member 6; Belongs to the cytochrome P450 family.
   
 0.744
NCOR1
Nuclear receptor corepressor 1.
    
 0.733
AHR
Uncharacterized protein.
   
 
 0.720
GBA
Glucosylceramidase.
      
 0.699
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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