STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (433 aa)    
Predicted Functional Partners:
AXIN1
Axin 1.
   
 0.998
CTNNB1
Catenin beta 1.
    
 0.998
AXIN2
Axin 2.
   
 0.993
APC
APC regulator of WNT signaling pathway.
    
 0.993
FRAT1
FRAT regulator of WNT signaling pathway 1.
    
 0.992
AKT1
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
0.991
MAPT
Microtubule-associated protein.
    
 0.990
BTRC
Beta-transducin repeat containing E3 ubiquitin protein ligase.
    
 0.979
APC2
APC regulator of WNT signaling pathway 2.
    
 0.979
DVL1
Dishevelled segment polarity protein 1.
   
 0.977
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.