Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ACTC1Actin alpha cardiac muscle 1. (377 aa)    
Predicted Functional Partners:
TNNT2
Troponin T2, cardiac type.
   
 0.985
ACTA1
Actin alpha 1, skeletal muscle.
  
 
0.981
TNNI3
Troponin I3, cardiac type.
   
 0.968
MYH6
Myosin heavy chain 6; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
   
 0.953
MYL2
Myosin light chain 2.
   
 0.951
TPM2
Uncharacterized protein; Belongs to the tropomyosin family.
   
 0.946
MYL3
Myosin light chain 3.
   
 0.946
TPM4
Tropomyosin 4; Belongs to the tropomyosin family.
   
 0.942
TPM1
Tropomyosin 1; Belongs to the tropomyosin family.
   
 0.933
MYL4
Myosin light chain 4.
   
 0.855
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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