STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TYK2Tyrosine-protein kinase. (1184 aa)    
Predicted Functional Partners:
IFNAR1
Interferon alpha and beta receptor subunit 1.
   
 0.999
STAT2
Signal transducer and activator of transcription.
   
 0.997
IL12RB1
Interleukin 12 receptor subunit beta 1.
   
 0.997
IFNAR2
Uncharacterized protein.
   
 0.996
STAT1
Signal transducer and activator of transcription.
   
 0.994
STAT3
Signal transducer and activator of transcription.
   
 0.994
IRF9
Interferon regulatory factor 9.
    
 0.991
IL13RA1
Interleukin 13 receptor subunit alpha 1.
    
 0.991
IL10RA
Interleukin 10 receptor subunit alpha.
   
 0.990
SOCS1
Suppressor of cytokine signaling 1.
    
 0.990
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.