STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LRRK2Leucine rich repeat kinase 2. (2527 aa)    
Predicted Functional Partners:
YWHAQ
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta; Belongs to the 14-3-3 family.
    
 0.800
DNM1L
Dynamin 1 like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
    
 0.783
SNCA
Alpha-synuclein; Belongs to the synuclein family.
   
 
 0.645
SFN
Stratifin; Belongs to the 14-3-3 family.
    
 0.603
VPS35
Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.
    
 
 0.590
EIF4EBP2
Eukaryotic translation initiation factor 4E binding protein 2.
    
 
 0.571
EIF4EBP3
Eukaryotic translation initiation factor 4E binding protein 3.
    
 
 0.571
PRKN
Parkin RBR E3 ubiquitin protein ligase.
    
 
 0.569
PARK7
Parkinsonism associated deglycase.
    
 
 0.559
PINK1
PTEN induced kinase 1.
      
 0.551
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.