STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SPTLC1Serine palmitoyltransferase long chain base subunit 1. (473 aa)    
Predicted Functional Partners:
SPTLC3
Serine palmitoyltransferase long chain base subunit 3.
  
0.998
SPTSSA
Serine palmitoyltransferase small subunit A.
    
 0.998
KDSR
3-ketodihydrosphingosine reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
 0.992
SPTLC2
Serine palmitoyltransferase long chain base subunit 2.
  
0.986
SPTSSB
Serine palmitoyltransferase small subunit B.
    
 0.984
ORMDL3
ORM1-like protein; Negative regulator of sphingolipid synthesis.
    
 0.975
ISM1
Isthmin 1.
   
 0.931
ISM2
Isthmin 2.
   
 0.866
ORMDL1
ORM1-like protein; Negative regulator of sphingolipid synthesis.
    
 
 0.863
SHMT2
Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family.
  
 
 0.846
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
Server load: low (30%) [HD]