Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MCF2MCF.2 cell line derived transforming sequence. (1070 aa)    
Predicted Functional Partners:
RHOA
Ras homolog family member A.
    
 0.896
CDC42
Cell division cycle 42.
    
 0.859
RHOC
Ras homolog family member C.
    
 0.795
RHOB
Ras homolog family member B.
    
 0.743
PLEK
Pleckstrin.
      
 0.730
PLEK2
Pleckstrin 2.
      
 0.714
RHOG
Ras homolog family member G.
    
 0.707
FPGS
Folylpolyglutamate synthase.
      
 0.698
ARHGEF1
Rho guanine nucleotide exchange factor 1.
     
 0.673
PEX3
Peroxisomal biogenesis factor 3.
      
 0.666
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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