Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
TMEM97Transmembrane protein 97; Intracellular orphan receptor that binds numerous drugs and which is highly expressed in various proliferating cells. Corresponds to the sigma-2 receptor, which is thought to play important role in regulating cell survival, morphology and differentiation. May play a role as a regulator of cellular cholesterol homeostasis. May function as sterol isomerase. May alter the activity of some cytochrome P450 proteins. (176 aa)    
Predicted Functional Partners:
PGRMC1
Progesterone receptor membrane component 1; Belongs to the cytochrome b5 family.
     
 0.891
PGRMC2
Progesterone receptor membrane component 2; Belongs to the cytochrome b5 family.
     
 0.825
SIGMAR1
Sigma non-opioid intracellular receptor 1.
   
  
 0.655
TMEM238
Transmembrane protein 238.
    
 
 0.623
TMEM94
Transmembrane protein 94.
      
 0.608
GLT8D2
Glycosyltransferase 8 domain containing 2.
      
 0.608
SMIM4
Small integral membrane protein 4.
      
 0.581
NPC1
NPC intracellular cholesterol transporter 1.
      
 0.581
SLC14A2
Solute carrier family 14 member 2.
    
 
 0.549
PDE10A
Phosphodiesterase.
    
 
 0.522
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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