Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FGD4FYVE, RhoGEF and PH domain containing 4. (660 aa)    
Predicted Functional Partners:
CDC42
Cell division cycle 42.
   
 0.754
FGD3
FYVE, RhoGEF and PH domain containing 3.
    
 0.724
SH3TC2
Uncharacterized protein.
      
 0.705
PIGN
Phosphatidylinositol glycan anchor biosynthesis class N.
   
    0.605
FAM234A
Family with sequence similarity 234 member A.
      
 0.576
FGD1
FYVE, RhoGEF and PH domain containing 1.
    
 0.522
ESAM
Endothelial cell adhesion molecule.
      
 0.519
RAC2
Rac family small GTPase 2.
   
 0.509
CD207
CD207 molecule.
   
  
 0.484
APEH
Acylaminoacyl-peptide hydrolase.
      
 0.481
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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