Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DENND5BDENN domain containing 5B. (1296 aa)    
Predicted Functional Partners:
DENND5A
DENN domain containing 5A.
   
   0.925
SLC24A3
Solute carrier family 24 member 3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
   
  
 0.762
ZMAT4
Zinc finger matrin-type 4.
   
  
 0.751
DENND4C
DENN domain containing 4C.
    
 
 0.747
ITFG1
Integrin alpha FG-GAP repeat containing 1.
      
 0.700
DENND3
DENN domain containing 3.
    
 
 0.694
DENND1C
DENN domain containing 1C.
    
 
 0.659
DENND4B
DENN domain containing 4B.
    
 
 0.654
PPL
Periplakin.
      
 0.644
EVPL
Envoplakin.
      
 0.628
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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