Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PARP15Poly [ADP-ribose] polymerase. (645 aa)    
Predicted Functional Partners:
IFIH1
Interferon induced with helicase C domain 1.
   
 
 0.745
PARP9
Poly(ADP-ribose) polymerase family member 9.
  
 
0.665
RNF213
Ring finger protein 213.
   
 0.617
PARP3
Poly [ADP-ribose] polymerase.
    
 
 0.543
PARP1
Poly(ADP-ribose) polymerase 1.
   
 
 0.542
PARP6
Poly [ADP-ribose] polymerase.
   
 
 0.513
PARP16
Poly [ADP-ribose] polymerase.
      
 0.510
PARP4
Poly [ADP-ribose] polymerase.
   
 
 0.505
RTP4
Receptor transporter protein 4.
   
  
 0.497
CDC42SE2
CDC42 small effector 2.
      
 0.495
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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