STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ARHGEF6Rac/Cdc42 guanine nucleotide exchange factor 6. (776 aa)    
Predicted Functional Partners:
PAK1
Non-specific serine/threonine protein kinase.
   
 0.998
GIT1
GIT ArfGAP 1.
   
 0.998
PAK2
Non-specific serine/threonine protein kinase.
   
 0.995
ARHGEF7
Rho guanine nucleotide exchange factor 7.
   
0.994
PAK3
Non-specific serine/threonine protein kinase.
   
 0.985
GIT2
GIT ArfGAP 2.
   
 0.981
RAC3
Rac family small GTPase 3.
   
 0.968
RAC2
Rac family small GTPase 2.
   
 0.964
RAC1
Rac family small GTPase 1.
   
 0.964
PAK4
Non-specific serine/threonine protein kinase.
    
 0.954
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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