Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
IL2RBInterleukin 2 receptor subunit beta. (551 aa)    
Predicted Functional Partners:
JAK1
Tyrosine-protein kinase.
   
 0.999
IL2
Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family.
    
 0.998
IL2RG
Fibronectin type-III domain-containing protein.
  
 0.998
IL2RA
Interleukin 2 receptor subunit alpha.
   
 0.998
IL15
Interleukin; Belongs to the IL-15/IL-21 family.
   
 0.995
JAK3
Tyrosine-protein kinase.
   
 0.992
STAT5A
Signal transducer and activator of transcription.
   
 0.975
IL7R
Interleukin 7 receptor.
   
 
 0.971
STAT5B
Signal transducer and activator of transcription.
   
 0.965
JAK2
Tyrosine-protein kinase.
   
 0.958
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
Server load: medium (50%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.