Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KSR1Kinase suppressor of ras 1. (851 aa)    
Predicted Functional Partners:
BRAP
BRCA1 associated protein.
    
 0.987
RAF1
Raf-1 proto-oncogene, serine/threonine kinase.
    
0.979
MAP2K1
Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily.
   
 0.957
MAP2K2
Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily.
   
 0.953
MARK3
Microtubule affinity regulating kinase 3.
   
 0.944
KSR2
Kinase suppressor of ras 2.
     
 
0.928
CD209
CD209 molecule.
    
 0.909
LSP1
Lymphocyte specific protein 1.
    
 0.883
PLK3
Serine/threonine-protein kinase PLK.
    
0.818
CNKSR2
Connector enhancer of kinase suppressor of Ras 2.
    
 0.812
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.