STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMPRSS6Transmembrane serine protease 6; Belongs to the peptidase S1 family. (800 aa)    
Predicted Functional Partners:
HJV
Hemojuvelin BMP co-receptor.
    
 
 0.736
TFR2
Transferrin receptor 2.
   
 
 0.661
HFE
Homeostatic iron regulator; Belongs to the MHC class I family.
      
 0.651
HAMP
Hepcidin antimicrobial peptide.
   
  
 0.632
TRIP10
Thyroid hormone receptor interactor 10.
    
 
 0.626
NEO1
Neogenin 1.
      
 0.626
DCN
Decorin; May affect the rate of fibrils formation.
    
 0.625
BMP6
Bone morphogenetic protein 6.
      
 0.618
IL1RAP
Interleukin 1 receptor accessory protein.
     
 0.547
PLOD2
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2.
      
 0.544
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.