STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TMPRSS6Transmembrane serine protease 6; Belongs to the peptidase S1 family. (800 aa)    
Predicted Functional Partners:
HJV
Hemojuvelin BMP co-receptor.
    
 
 0.925
DCN
Decorin; May affect the rate of fibrils formation.
   
 0.801
HAMP
Hepcidin antimicrobial peptide.
   
  
 0.721
HFE
Homeostatic iron regulator; Belongs to the MHC class I family.
     
 0.648
BOP1
Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
      
 0.641
TFR2
Transferrin receptor 2.
   
  
 0.621
BMP6
Bone morphogenetic protein 6.
     
 0.556
TFRC
Transferrin receptor.
   
  
 0.538
SLC25A28
Solute carrier family 25 member 28; Belongs to the mitochondrial carrier (TC 2.A.29) family.
      
 0.493
NEO1
Neogenin 1.
    
 
 0.486
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.