CHAC1 protein (Chlorocebus sabaeus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

CHAC1

Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (222 aa)

Predicted Functional Partners:

GPX4

0.928

GGCT

0.928

OPLAH

0.921

GPX7

0.916

GGT6

0.912

GPX5

0.910

GSS

0.910

ENSCSAP00000006952

0.908

GGT5

0.908

GGT7

0.908

Your Current Organism:

Chlorocebus sabaeus

NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CHAC1	ENSCSAP00000006952	ENSCSAP00000003886	ENSCSAP00000006952	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.	Uncharacterized protein.	0.908
CHAC1	GGCT	ENSCSAP00000003886	ENSCSAP00000010646	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.	Uncharacterized protein.	0.928
CHAC1	GGT5	ENSCSAP00000003886	ENSCSAP00000006966	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.	Gamma-glutamyltransferase 5.	0.908
CHAC1	GGT6	ENSCSAP00000003886	ENSCSAP00000009326	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.	Gamma-glutamyltransferase 6.	0.912
CHAC1	GGT7	ENSCSAP00000003886	ENSCSAP00000008154	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.	Gamma-glutamyltransferase 7.	0.908
CHAC1	GPX4	ENSCSAP00000003886	ENSCSAP00000008514	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.	Uncharacterized protein.	0.928
CHAC1	GPX5	ENSCSAP00000003886	ENSCSAP00000004311	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	0.910
CHAC1	GPX7	ENSCSAP00000003886	ENSCSAP00000016737	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	0.916
CHAC1	GSS	ENSCSAP00000003886	ENSCSAP00000008059	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.	Glutathione synthetase.	0.910
CHAC1	OPLAH	ENSCSAP00000003886	ENSCSAP00000005071	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.	5-oxoprolinase, ATP-hydrolysing.	0.921
ENSCSAP00000006952	CHAC1	ENSCSAP00000006952	ENSCSAP00000003886	Uncharacterized protein.	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.	0.908
ENSCSAP00000006952	GGCT	ENSCSAP00000006952	ENSCSAP00000010646	Uncharacterized protein.	Uncharacterized protein.	0.954
ENSCSAP00000006952	GGT5	ENSCSAP00000006952	ENSCSAP00000006966	Uncharacterized protein.	Gamma-glutamyltransferase 5.	0.980
ENSCSAP00000006952	GGT6	ENSCSAP00000006952	ENSCSAP00000009326	Uncharacterized protein.	Gamma-glutamyltransferase 6.	0.955
ENSCSAP00000006952	GGT7	ENSCSAP00000006952	ENSCSAP00000008154	Uncharacterized protein.	Gamma-glutamyltransferase 7.	0.966
ENSCSAP00000006952	GPX4	ENSCSAP00000006952	ENSCSAP00000008514	Uncharacterized protein.	Uncharacterized protein.	0.909
ENSCSAP00000006952	GPX5	ENSCSAP00000006952	ENSCSAP00000004311	Uncharacterized protein.	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	0.907
ENSCSAP00000006952	GPX7	ENSCSAP00000006952	ENSCSAP00000016737	Uncharacterized protein.	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	0.909
ENSCSAP00000006952	GSS	ENSCSAP00000006952	ENSCSAP00000008059	Uncharacterized protein.	Glutathione synthetase.	0.963
ENSCSAP00000006952	OPLAH	ENSCSAP00000006952	ENSCSAP00000005071	Uncharacterized protein.	5-oxoprolinase, ATP-hydrolysing.	0.919

page 1 of 5

Server load: low (24%) [HD]

Permalink

Network

Neighborhood

Experiments

Co-occurrence

Databases

Co-expression

Textmining

Fusion

© STRING Consortium 2026

Credits

Access

Info

About