STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RNF144BRBR-type E3 ubiquitin transferase. (303 aa)    
Predicted Functional Partners:
PRKDC
Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family.
    
 0.827
RNF216
Ring finger protein 216.
   
 0.618
UBE2L6
Ubiquitin conjugating enzyme E2 L6; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.574
TBK1
TANK binding kinase 1.
   
  0.572
CDKN1A
Cyclin dependent kinase inhibitor 1A.
    
 
 0.535
UBA52
Ubiquitin A-52 residue ribosomal protein fusion product 1.
    
  0.523
PRIM2
DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands.
      
 0.523
ENSCSAP00000018444
Ubiquitin-like domain-containing protein.
    
  0.523
FAM120A
Family with sequence similarity 120A.
      
 0.520
SMYD4
SET and MYND domain containing 4.
      
 0.520
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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