Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
CAPN1Calpain 1; Belongs to the peptidase C2 family. (816 aa)    
Predicted Functional Partners:
CAPN2
Calpain 2; Belongs to the peptidase C2 family.
  
0.985
CAST
Calpastatin.
   
 0.984
CDK5R1
Cyclin-dependent kinase 5 activator.
   
 0.942
CAPNS1
Calpain small subunit 1.
   
 0.941
CASP12
Caspase 12 (gene/pseudogene); Belongs to the peptidase C14A family.
    
 0.914
BID
BH3-interacting domain death agonist; Counters the protective effect of Bcl-2.
    
 0.909
BAX
BCL2 associated X, apoptosis regulator.
   
 0.909
BAK1
BCL2 antagonist/killer 1.
   
 0.905
IL1A
Interleukin-1; Belongs to the IL-1 family.
   
 
 0.903
CAPN8
Calpain 8; Belongs to the peptidase C2 family.
   
 0.839
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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