STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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CACNG2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (323 aa)    
Predicted Functional Partners:
GRIA1
Glutamate ionotropic receptor AMPA type subunit 1.
   
 0.967
DLG4
Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family.
   
 0.949
GRIA2
Glutamate ionotropic receptor AMPA type subunit 2.
   
 0.923
GRIA4
Glutamate ionotropic receptor AMPA type subunit 4.
   
 0.908
GRIA3
Glutamate ionotropic receptor AMPA type subunit 3.
   
 0.865
DRD2
Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family.
   
  
 0.863
CACNB4
Calcium voltage-gated channel auxiliary subunit beta 4.
     
 0.840
CACNG8
Voltage-dependent calcium channel gamma-8 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
  
 
 
0.831
CACNB3
Calcium voltage-gated channel auxiliary subunit beta 3.
     
 0.807
CACNA2D2
Calcium voltage-gated channel auxiliary subunit alpha2delta 2.
   
 
 0.792
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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