Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MAP3K11Mitogen-activated protein kinase kinase kinase 11. (614 aa)    
Predicted Functional Partners:
CDC42
Cell division cycle 42.
   
 0.987
MAPK8IP1
Mitogen-activated protein kinase 8 interacting protein 1.
    
 0.968
MAP2K7
Mitogen-activated protein kinase kinase 7.
   
0.965
MAPK8IP2
Mitogen-activated protein kinase 8 interacting protein 2.
    
 0.958
MAP4K1
Mitogen-activated protein kinase kinase kinase kinase 1; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.
    
0.948
RAC1
Rac family small GTPase 1.
   
 0.937
MAPK8IP3
Mitogen-activated protein kinase 8 interacting protein 3.
    
 0.931
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.696
GRIK2
Glutamate ionotropic receptor kainate type subunit 2.
   
 
 0.678
MRPL30
Ribosomal_L30 domain-containing protein.
      
 0.669
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.