| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ENSCSAP00000003525 | PPAN | ENSCSAP00000003525 | ENSCSAP00000003686 | Uncharacterized protein; Belongs to the universal ribosomal protein uL3 family. | Peter pan homolog. | 0.410 |
| ENSCSAP00000003525 | RRP8 | ENSCSAP00000003525 | ENSCSAP00000000691 | Uncharacterized protein; Belongs to the universal ribosomal protein uL3 family. | Ribosomal RNA-processing protein 8; Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone- modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and pr [...] | 0.645 |
| ENSCSAP00000003525 | ZNF184 | ENSCSAP00000003525 | ENSCSAP00000004218 | Uncharacterized protein; Belongs to the universal ribosomal protein uL3 family. | Zinc finger protein 184. | 0.402 |
| ENSCSAP00000018184 | PPAN | ENSCSAP00000018184 | ENSCSAP00000003686 | Uncharacterized protein; Belongs to the universal ribosomal protein uL3 family. | Peter pan homolog. | 0.410 |
| ENSCSAP00000018184 | RRP8 | ENSCSAP00000018184 | ENSCSAP00000000691 | Uncharacterized protein; Belongs to the universal ribosomal protein uL3 family. | Ribosomal RNA-processing protein 8; Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone- modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and pr [...] | 0.645 |
| ENSCSAP00000018184 | ZNF184 | ENSCSAP00000018184 | ENSCSAP00000004218 | Uncharacterized protein; Belongs to the universal ribosomal protein uL3 family. | Zinc finger protein 184. | 0.402 |
| ENSCSAP00000019107 | PPAN | ENSCSAP00000019107 | ENSCSAP00000003686 | Uncharacterized protein; Belongs to the universal ribosomal protein uL3 family. | Peter pan homolog. | 0.410 |
| ENSCSAP00000019107 | RRP8 | ENSCSAP00000019107 | ENSCSAP00000000691 | Uncharacterized protein; Belongs to the universal ribosomal protein uL3 family. | Ribosomal RNA-processing protein 8; Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone- modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and pr [...] | 0.645 |
| ENSCSAP00000019107 | ZNF184 | ENSCSAP00000019107 | ENSCSAP00000004218 | Uncharacterized protein; Belongs to the universal ribosomal protein uL3 family. | Zinc finger protein 184. | 0.402 |
| PPAN | ENSCSAP00000003525 | ENSCSAP00000003686 | ENSCSAP00000003525 | Peter pan homolog. | Uncharacterized protein; Belongs to the universal ribosomal protein uL3 family. | 0.410 |
| PPAN | ENSCSAP00000018184 | ENSCSAP00000003686 | ENSCSAP00000018184 | Peter pan homolog. | Uncharacterized protein; Belongs to the universal ribosomal protein uL3 family. | 0.410 |
| PPAN | ENSCSAP00000019107 | ENSCSAP00000003686 | ENSCSAP00000019107 | Peter pan homolog. | Uncharacterized protein; Belongs to the universal ribosomal protein uL3 family. | 0.410 |
| PPAN | RRP8 | ENSCSAP00000003686 | ENSCSAP00000000691 | Peter pan homolog. | Ribosomal RNA-processing protein 8; Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone- modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and pr [...] | 0.688 |
| PPAN | ZNF184 | ENSCSAP00000003686 | ENSCSAP00000004218 | Peter pan homolog. | Zinc finger protein 184. | 0.438 |
| RRP8 | ENSCSAP00000003525 | ENSCSAP00000000691 | ENSCSAP00000003525 | Ribosomal RNA-processing protein 8; Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone- modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and pr [...] | Uncharacterized protein; Belongs to the universal ribosomal protein uL3 family. | 0.645 |
| RRP8 | ENSCSAP00000018184 | ENSCSAP00000000691 | ENSCSAP00000018184 | Ribosomal RNA-processing protein 8; Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone- modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and pr [...] | Uncharacterized protein; Belongs to the universal ribosomal protein uL3 family. | 0.645 |
| RRP8 | ENSCSAP00000019107 | ENSCSAP00000000691 | ENSCSAP00000019107 | Ribosomal RNA-processing protein 8; Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone- modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and pr [...] | Uncharacterized protein; Belongs to the universal ribosomal protein uL3 family. | 0.645 |
| RRP8 | PPAN | ENSCSAP00000000691 | ENSCSAP00000003686 | Ribosomal RNA-processing protein 8; Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone- modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and pr [...] | Peter pan homolog. | 0.688 |
| RRP8 | ZNF184 | ENSCSAP00000000691 | ENSCSAP00000004218 | Ribosomal RNA-processing protein 8; Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone- modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and pr [...] | Zinc finger protein 184. | 0.447 |
| TRIM28 | ZNF184 | ENSCSAP00000016435 | ENSCSAP00000004218 | Tripartite motif containing 28. | Zinc finger protein 184. | 0.627 |