STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IAPPIslet amyloid polypeptide. (89 aa)    
Predicted Functional Partners:
CALCR
Calcitonin receptor; Belongs to the G-protein coupled receptor 2 family.
    
 0.992
CALCRL
Calcitonin receptor like receptor; Belongs to the G-protein coupled receptor 2 family.
    
 0.982
ADM
Adrenomedullin.
     
 0.965
CALCB
Calcitonin related polypeptide beta.
     
 0.955
CALCA
Calcitonin related polypeptide alpha.
     
 0.950
RAMP1
Receptor activity modifying protein 1.
    
 0.948
RAMP2
Receptor activity modifying protein 2.
    
 0.946
RAMP3
Receptor activity modifying protein 3.
    
 0.932
IDE
Insulin degrading enzyme; Belongs to the peptidase M16 family.
    
 
 0.907
INS
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
   
 
 0.779
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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