Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DESDesmin; Belongs to the intermediate filament family. (470 aa)    
Predicted Functional Partners:
VIM
Vimentin; Belongs to the intermediate filament family.
   
  0.981
GFAP
Glial fibrillary acidic protein; Belongs to the intermediate filament family.
   
  0.910
PRPH
Peripherin; Belongs to the intermediate filament family.
   
   0.909
NEFL
Neurofilament light; Belongs to the intermediate filament family.
   
 
 0.903
NEFM
Neurofilament medium; Belongs to the intermediate filament family.
   
 
 0.895
SYNC
Syncoilin, intermediate filament protein; Belongs to the intermediate filament family.
   
 
 0.889
KRT7
Keratin 7; Belongs to the intermediate filament family.
    
   0.873
SYNM
Synemin; Belongs to the intermediate filament family.
   
 
 0.789
NES
Nestin; Belongs to the intermediate filament family.
    
 
 0.711
GAN
Gigaxonin.
    
 
 0.677
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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