Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
SDC1Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (310 aa)    
Predicted Functional Partners:
HPSE
Heparanase.
     
 0.995
SDC4
Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.
   
0.985
HPSE2
Uncharacterized protein.
     
 0.981
GPC1
Glypican 1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.
    
 0.981
THBS1
Thrombospondin 1.
    
 0.966
ITGB3
Integrin beta; Belongs to the integrin beta chain family.
    
 0.963
ITGAV
Integrin subunit alpha V; Belongs to the integrin alpha chain family.
     
 0.952
MMP9
Matrix metallopeptidase 9.
    
 0.942
SDC2
Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.
  
  
0.913
THBS4
Thrombospondin 4.
    
 0.910
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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