STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AIFM2Apoptosis inducing factor mitochondria associated 2. (373 aa)    
Predicted Functional Partners:
CDKAL1
CDK5 regulatory subunit associated protein 1 like 1.
      
 0.740
TMLHE
Trimethyllysine hydroxylase, epsilon.
      
 0.730
LDHC
L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.
   
  
 0.674
TP53
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
 0.634
GPX4
Uncharacterized protein.
   
  
 0.596
SUOX
Sulfite oxidase.
  
 0.568
GSR
Glutathione-disulfide reductase.
  
 0.567
GLDC
Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine.
   
 
 0.540
MRPS5
Mitochondrial ribosomal protein S5; Belongs to the universal ribosomal protein uS5 family.
   
 
 0.528
PIPOX
Pipecolic acid and sarcosine oxidase.
  
 0.523
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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