STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PRF1Perforin 1. (555 aa)    
Predicted Functional Partners:
GNLY
Saposin B-type domain-containing protein.
   
 
 0.971
GZMB
Granzyme B; Belongs to the peptidase S1 family.
   
 0.968
GZMA
Granzyme A; Belongs to the peptidase S1 family.
   
 0.967
NKG7
Natural killer cell granule protein 7.
   
  
 0.948
KLRD1
Uncharacterized protein.
   
 0.935
CD8A
CD8a molecule.
   
  
 0.899
IL2RB
Interleukin 2 receptor subunit beta.
   
  
 0.898
GZMH
Granzyme H; Belongs to the peptidase S1 family.
   
 0.898
CTSW
Cathepsin W; Belongs to the peptidase C1 family.
   
 
 0.848
FASLG
Fas ligand; Belongs to the tumor necrosis factor family.
   
 0.779
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.