STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACTN3Actinin alpha 3 (gene/pseudogene). (901 aa)    
Predicted Functional Partners:
ACTN2
Actinin alpha 2.
  
0.945
MYOZ1
Myozenin 1.
   
 
 0.932
MYLPF
Myosin light chain, phosphorylatable, fast skeletal muscle.
   
 0.847
TNNT3
Troponin T3, fast skeletal type.
   
 0.799
CASQ1
Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle.
   
 0.768
MYH4
Myosin heavy chain 4; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
   
 0.762
TNNC2
Troponin C2, fast skeletal type.
   
 0.745
DERL3
Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.
      
 0.741
TNNI2
Troponin I2, fast skeletal type.
   
 0.733
AMPD1
AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.
   
 
 0.731
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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