STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PDE6HPhosphodiesterase 6H. (83 aa)    
Predicted Functional Partners:
HPRT1
Hypoxanthine phosphoribosyltransferase 1.
     
  0.900
GMPS
Guanine monophosphate synthase.
     
  0.900
GUK1
Guanylate kinase 1.
     
  0.900
PDE6C
Phosphodiesterase.
   
 
 0.766
KCNV2
Potassium voltage-gated channel modifier subfamily V member 2; Belongs to the potassium channel family.
   
  
 0.757
GNGT2
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
      
 0.731
CNGA1
Cyclic nucleotide gated channel subunit alpha 1.
   
  
 0.727
GUCY2D
Guanylate cyclase.
     
 0.722
GNAT2
G protein subunit alpha transducin 2.
   
 
 0.712
GUCY2F
Guanylate cyclase.
     
 0.709
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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