STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (411 aa)    
Predicted Functional Partners:
PTCH1
Patched 1.
   
 0.994
HHIP
Hedgehog interacting protein.
    
 0.992
PTCH2
Patched 2.
   
 0.991
BOC
BOC cell adhesion associated, oncogene regulated.
    
 0.987
CDON
Cell adhesion associated, oncogene regulated.
    
 0.987
GPC3
Uncharacterized protein; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.
    
 0.976
DISP1
SSD domain-containing protein.
   
 0.970
GAS1
Growth arrest specific 1.
    
 0.958
SHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
  
 
0.938
DHH
Desert hedgehog signaling molecule.
  
  
0.933
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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