STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RCE1Ras converting CAAX endopeptidase 1. (329 aa)    
Predicted Functional Partners:
ICMT
Protein-S-isoprenylcysteine O-methyltransferase.
   
 0.945
ZMPSTE24
CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family.
    
 
 0.920
USP42
Ubiquitin specific peptidase 42; Belongs to the peptidase C19 family.
     
 0.812
FNTA
Farnesyltransferase, CAAX box, alpha.
     
 0.794
COG6
Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function.
    
   0.724
FNTB
Protein farnesyltransferase subunit beta; Essential subunit of the farnesyltransferase complex. Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X.
    
 0.706
CHURC1
Churchill domain containing 1.
    
 0.706
USP36
Ubiquitin specific peptidase 36; Belongs to the peptidase C19 family.
     
 0.705
CDC25A
Cell division cycle 25A.
     
 0.685
RCC1
Regulator of chromosome condensation 1.
      
 0.675
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.