STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PSAPProsaposin; Prosaposin: Behaves as a myelinotrophic and neurotrophic factor, these effects are mediated by its G-protein-coupled receptors, GPR37 and GPR37L1, undergoing ligand-mediated internalization followed by ERK phosphorylation signaling. (524 aa)    
Predicted Functional Partners:
PSAPL1
Proactivator polypeptide-like 1; May activate the lysosomal degradation of sphingolipids.
     
 
0.900
GPR37
G protein-coupled receptor 37.
     
 0.897
GLA
Alpha-galactosidase.
   
 0.888
GBA
Glucosylceramidase.
   
 0.879
GPR37L1
G protein-coupled receptor 37 like 1.
     
 0.860
ARSA
Arylsulfatase A.
     
 0.770
NAGA
Alpha-galactosidase.
   
 0.738
GALC
Galactosylceramidase.
    
 
 0.733
GM2A
GM2 ganglioside activator.
   
 
 0.702
HEXB
Beta-hexosaminidase.
   
 
 0.695
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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