RAD9A protein (Chlorocebus sabaeus) - STRING interaction network

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RAD9A

Cell cycle checkpoint control protein; Belongs to the rad9 family. (390 aa)

Predicted Functional Partners:

RAD1

0.999

ATR

0.990

HUS1

0.990

RAD17

0.987

TOPBP1

0.978

RAD9B

0.941

RFC2

0.932

RFC5

0.910

ATM

0.901

RHNO1

0.895

Your Current Organism:

Chlorocebus sabaeus

NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATM	ATR	ENSCSAP00000015071	ENSCSAP00000007482	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	0.995
ATM	HUS1	ENSCSAP00000015071	ENSCSAP00000011876	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	Checkpoint protein; Belongs to the HUS1 family.	0.863
ATM	RAD1	ENSCSAP00000015071	ENSCSAP00000013157	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	RAD1 checkpoint DNA exonuclease.	0.919
ATM	RAD17	ENSCSAP00000015071	ENSCSAP00000011811	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	RAD17 checkpoint clamp loader component.	0.954
ATM	RAD9A	ENSCSAP00000015071	ENSCSAP00000004797	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	Cell cycle checkpoint control protein; Belongs to the rad9 family.	0.901
ATM	RAD9B	ENSCSAP00000015071	ENSCSAP00000015395	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	Cell cycle checkpoint control protein; Belongs to the rad9 family.	0.864
ATM	RFC2	ENSCSAP00000015071	ENSCSAP00000014213	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	Replication factor C subunit 2.	0.847
ATM	RFC5	ENSCSAP00000015071	ENSCSAP00000015721	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	Replication factor C subunit 5.	0.697
ATM	RHNO1	ENSCSAP00000015071	ENSCSAP00000007462	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	RAD9-HUS1-RAD1 interacting nuclear orphan 1.	0.566
ATM	TOPBP1	ENSCSAP00000015071	ENSCSAP00000006889	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	DNA topoisomerase II binding protein 1.	0.942
ATR	ATM	ENSCSAP00000007482	ENSCSAP00000015071	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	0.995
ATR	HUS1	ENSCSAP00000007482	ENSCSAP00000011876	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	Checkpoint protein; Belongs to the HUS1 family.	0.990
ATR	RAD1	ENSCSAP00000007482	ENSCSAP00000013157	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	RAD1 checkpoint DNA exonuclease.	0.987
ATR	RAD17	ENSCSAP00000007482	ENSCSAP00000011811	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	RAD17 checkpoint clamp loader component.	0.966
ATR	RAD9A	ENSCSAP00000007482	ENSCSAP00000004797	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	Cell cycle checkpoint control protein; Belongs to the rad9 family.	0.990
ATR	RAD9B	ENSCSAP00000007482	ENSCSAP00000015395	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	Cell cycle checkpoint control protein; Belongs to the rad9 family.	0.981
ATR	RFC2	ENSCSAP00000007482	ENSCSAP00000014213	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	Replication factor C subunit 2.	0.814
ATR	RFC5	ENSCSAP00000007482	ENSCSAP00000015721	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	Replication factor C subunit 5.	0.651
ATR	RHNO1	ENSCSAP00000007482	ENSCSAP00000007462	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	RAD9-HUS1-RAD1 interacting nuclear orphan 1.	0.648
ATR	TOPBP1	ENSCSAP00000007482	ENSCSAP00000006889	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	DNA topoisomerase II binding protein 1.	0.981

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