DEPDC5 protein (Chlorocebus sabaeus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

DEPDC5

DEP domain-containing protein. (1594 aa)

Predicted Functional Partners:

WDR59

0.999

WDR24

0.999

MIOS

0.999

NPRL3

0.999

NPRL2

0.999

SEC13

0.996

RRAGB

0.996

SEH1L

0.996

ITFG2

0.985

RRAGC

0.985

Your Current Organism:

Chlorocebus sabaeus

NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DEPDC5	ITFG2	ENSCSAP00000004829	ENSCSAP00000007494	DEP domain-containing protein.	Integrin alpha FG-GAP repeat containing 2.	0.985
DEPDC5	MIOS	ENSCSAP00000004829	ENSCSAP00000009257	DEP domain-containing protein.	Meiosis regulator for oocyte development.	0.999
DEPDC5	NPRL2	ENSCSAP00000004829	ENSCSAP00000010329	DEP domain-containing protein.	NPR2 like, GATOR1 complex subunit.	0.999
DEPDC5	NPRL3	ENSCSAP00000004829	ENSCSAP00000009307	DEP domain-containing protein.	NPR3 like, GATOR1 complex subunit.	0.999
DEPDC5	RRAGB	ENSCSAP00000004829	ENSCSAP00000008271	DEP domain-containing protein.	Ras related GTP binding B.	0.996
DEPDC5	RRAGC	ENSCSAP00000004829	ENSCSAP00000016890	DEP domain-containing protein.	Ras related GTP binding C.	0.985
DEPDC5	SEC13	ENSCSAP00000004829	ENSCSAP00000006264	DEP domain-containing protein.	SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family.	0.996
DEPDC5	SEH1L	ENSCSAP00000004829	ENSCSAP00000013524	DEP domain-containing protein.	SEH1 like nucleoporin; Belongs to the WD repeat SEC13 family.	0.996
DEPDC5	WDR24	ENSCSAP00000004829	ENSCSAP00000008444	DEP domain-containing protein.	WD repeat domain 24.	0.999
DEPDC5	WDR59	ENSCSAP00000004829	ENSCSAP00000000918	DEP domain-containing protein.	WD repeat domain 59.	0.999
ITFG2	DEPDC5	ENSCSAP00000007494	ENSCSAP00000004829	Integrin alpha FG-GAP repeat containing 2.	DEP domain-containing protein.	0.985
ITFG2	MIOS	ENSCSAP00000007494	ENSCSAP00000009257	Integrin alpha FG-GAP repeat containing 2.	Meiosis regulator for oocyte development.	0.685
ITFG2	NPRL2	ENSCSAP00000007494	ENSCSAP00000010329	Integrin alpha FG-GAP repeat containing 2.	NPR2 like, GATOR1 complex subunit.	0.986
ITFG2	NPRL3	ENSCSAP00000007494	ENSCSAP00000009307	Integrin alpha FG-GAP repeat containing 2.	NPR3 like, GATOR1 complex subunit.	0.826
ITFG2	RRAGB	ENSCSAP00000007494	ENSCSAP00000008271	Integrin alpha FG-GAP repeat containing 2.	Ras related GTP binding B.	0.581
ITFG2	RRAGC	ENSCSAP00000007494	ENSCSAP00000016890	Integrin alpha FG-GAP repeat containing 2.	Ras related GTP binding C.	0.502
ITFG2	SEC13	ENSCSAP00000007494	ENSCSAP00000006264	Integrin alpha FG-GAP repeat containing 2.	SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family.	0.606
ITFG2	SEH1L	ENSCSAP00000007494	ENSCSAP00000013524	Integrin alpha FG-GAP repeat containing 2.	SEH1 like nucleoporin; Belongs to the WD repeat SEC13 family.	0.629
ITFG2	WDR24	ENSCSAP00000007494	ENSCSAP00000008444	Integrin alpha FG-GAP repeat containing 2.	WD repeat domain 24.	0.977
ITFG2	WDR59	ENSCSAP00000007494	ENSCSAP00000000918	Integrin alpha FG-GAP repeat containing 2.	WD repeat domain 59.	0.975

page 1 of 6

Server load: medium (58%) [HD]

Permalink

Network

Cooccurrence

Experiments

Coexpression

Databases

Neighborhood

Textmining

Fusion

© STRING Consortium 2025

Credits

Access

Info

About