Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SEC61A1SEC61 translocon alpha 1 subunit. (423 aa)    
Predicted Functional Partners:
SEC61B
Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.
   
 0.991
SEC61G
SEC61 translocon gamma subunit.
   
 0.989
SEC63
SEC63 homolog, protein translocation regulator.
   
 
 0.973
RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...]
   
 0.927
RPS9
S4 RNA-binding domain-containing protein; Belongs to the universal ribosomal protein uS4 family.
  
 
 0.909
RPL35
Uncharacterized protein.
  
 
 0.905
RPS20
Ribosomal_S10 domain-containing protein.
  
 
 0.904
SEC61A2
SEC61 translocon alpha 2 subunit.
  
  
 
0.900
RPS29
Uncharacterized protein.
  
 
 0.897
RPL23
Uncharacterized protein; Belongs to the universal ribosomal protein uL14 family.
  
 
 0.890
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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