STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DOCK8Dedicator of cytokinesis 8; Belongs to the DOCK family. (2098 aa)    
Predicted Functional Partners:
LRCH1
Leucine rich repeats and calponin homology domain containing 1.
   
 
 0.925
LRCH4
Leucine rich repeats and calponin homology domain containing 4.
   
 
 0.920
LRCH3
Leucine rich repeats and calponin homology domain containing 3.
   
 
 0.908
DOCK6
DHR-2 domain-containing protein; Belongs to the DOCK family.
    
   0.873
RHOJ
Ras homolog family member J.
   
 0.841
DOCK7
Dedicator of cytokinesis 7; Belongs to the DOCK family.
    
   0.825
CDC42
Cell division cycle 42.
   
 0.821
ENSCSAP00000017383
Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
    
 
 0.812
LRCH2
Leucine rich repeats and calponin homology domain containing 2.
   
 
 0.808
INPP5D
Inositol polyphosphate-5-phosphatase D.
   
  
 0.800
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.