Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PDLIM7PDZ and LIM domain 7. (423 aa)    
Predicted Functional Partners:
PDLIM5
PDZ and LIM domain 5.
    
 
0.915
LDB3
LIM domain binding 3.
   
 
0.907
WWP2
E3 ubiquitin-protein ligase.
   
   0.790
SMURF1
E3 ubiquitin-protein ligase.
   
 
 0.770
ZMYND11
Zinc finger MYND-type containing 11.
    
   0.748
RET
Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands.
   
 0.729
TPM2
Uncharacterized protein; Belongs to the tropomyosin family.
   
 0.643
PDLIM3
PDZ and LIM domain 3.
   
 
0.630
PDLIM4
PDZ and LIM domain 4.
   
 
0.623
PDLIM1
PDZ and LIM domain 1.
   
 
0.615
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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