STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
F12Coagulation factor XII. (615 aa)    
Predicted Functional Partners:
SERPING1
Serpin family G member 1; Belongs to the serpin family.
   
 0.929
KLKB1
Kallikrein B1; Belongs to the peptidase S1 family.
  
0.899
KNG1
Kininogen 1.
   
 0.892
IGFALS
Insulin like growth factor binding protein acid labile subunit.
   
 0.884
C6
Complement C6.
   
 
 0.860
C1QBP
Complement C1q binding protein.
    
 0.818
C7
Complement C7.
   
 
 0.818
HGF
Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.
   
 0.785
SPINT1
Serine peptidase inhibitor, Kunitz type 1.
    
 0.778
GP1BA
Glycoprotein Ib platelet subunit alpha.
    
 0.752
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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