STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAK3Non-specific serine/threonine protein kinase. (559 aa)    
Predicted Functional Partners:
CDC42
Cell division cycle 42.
   
 0.992
ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor 6.
    
 0.990
ARHGEF7
Rho guanine nucleotide exchange factor 7.
    
 0.986
NCK1
Cytoplasmic protein.
    
 0.970
NCK2
Cytoplasmic protein.
    
 0.967
RAC2
Rac family small GTPase 2.
   
 0.964
RAC3
Rac family small GTPase 3.
   
 0.964
LIMK1
LIM domain kinase 1.
    
0.955
LIMK2
LIM domain kinase 2.
    
0.952
MYO6
Myosin VI; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
    
  0.937
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.