Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
C2Uncharacterized protein; Belongs to the peptidase S1 family. (1266 aa)    
Predicted Functional Partners:
ENSCSAP00000009714
Uncharacterized protein.
   
 0.975
C3
Complement C3.
   
 0.974
CFD
Complement factor D; Belongs to the peptidase S1 family.
   
0.969
C5
Complement C5.
   
 0.861
C4B
Uncharacterized protein.
   
 0.816
CFI
Complement factor I; Belongs to the peptidase S1 family.
   
 
0.804
ENSCSAP00000003709
Anaphylatoxin-like domain-containing protein.
   
 0.752
CFP
Complement factor properdin.
   
 0.710
GZMK
Granzyme K; Belongs to the peptidase S1 family.
   
 0.706
CFHR2
Complement factor H related 2.
   
 0.663
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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