STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MLANAMelan-A. (118 aa)    
Predicted Functional Partners:
TYR
Tyrosinase.
   
  
 0.956
DCT
Dopachrome tautomerase.
   
  
 0.904
GPR143
G protein-coupled receptor 143.
   
 
 0.769
HLA-DRA
Major histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family.
    
   0.743
MITF
Melanocyte inducing transcription factor.
    
 0.688
SLC45A2
Solute carrier family 45 member 2.
   
  
 0.666
SLC24A5
Solute carrier family 24 member 5; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
   
  
 0.627
TRPM1
Transient receptor potential cation channel subfamily M member 1.
   
  
 0.574
NEDD4
E3 ubiquitin-protein ligase.
    
   0.557
ITCH
E3 ubiquitin-protein ligase.
    
   0.557
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
Server load: low (16%) [HD]